New Indications for Liver Transplantation

Alberto Zanetto; Sarah Shalaby; Martina Gambato; Giacomo Germani; Marco Senzolo; Debora Bizzaro; Francesco Paolo Russo; Patrizia Burra

doi:10.3390/jcm10173867

Journal of Clinical Medicine (Aug 2021)

New Indications for Liver Transplantation

Alberto Zanetto,
Sarah Shalaby,
Martina Gambato,
Giacomo Germani,
Marco Senzolo,
Debora Bizzaro,
Francesco Paolo Russo,
Patrizia Burra

Affiliations

Alberto Zanetto: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Sarah Shalaby: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Martina Gambato: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Giacomo Germani: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Marco Senzolo: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Debora Bizzaro: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Francesco Paolo Russo: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Patrizia Burra: Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy

DOI: https://doi.org/10.3390/jcm10173867
Journal volume & issue: Vol. 10, no. 17
p. 3867

Abstract

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Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases.

Published in Journal of Clinical Medicine

ISSN: 2077-0383 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/jcm

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