Neuropsychiatric Disease and Treatment (Feb 2020)
Affective Symptoms and Health-Related Quality of Life Among Women with Stress Urinary Incontinence: Cross-Sectional Study
Abstract
Vesta Steibliene,1,2 Rosita Aniuliene,3 Povilas Aniulis,4 Nijole Raskauskiene,2 Virginija Adomaitiene1 1Clinic of Psychiatry, Lithuanian University of Health Sciences, Kaunas, Lithuania; 2Neuroscience Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania; 3Department of Obstetrics and Gynaecology, Lithuanian University of Health Sciences, Kaunas, Lithuania; 4Department of Urology, Lithuanian University of Health Sciences, Kaunas, LithuaniaCorrespondence: Vesta SteiblieneLithuanian University of Health Sciences, Mickeviciaus Str. 9, Kaunas LT432060, LithuaniaTel +370 687 39116Fax +370 460 30011Email [email protected]: To evaluate the relationship between affective symptoms, clinical variables of uro-gynaecological history and health-related quality of life (QoL) among women with stress urinary incontinence (SUI) in comparison to healthy controls.Patients and Methods: In a cross-sectional study, 80 women 30 to 80 years of age diagnosed with SUI and 97 controls without symptoms of SUI provided sociodemographic data and answered the King’s Health Questionnaire (KHQ) for assessing the QoL among individuals with urinary incontinence. Symptoms of anxiety and depression were assessed by Hospital Anxiety and Depression (HAD) scale with a threshold ≥ 7. A multiple regression was performed to reveal the cross-sectional predictors of affective symptoms and QoL among women with SUI.Results: Women with SUI had a significantly higher prevalence of symptoms of anxiety and depression than the controls (50% vs 11% and 29% vs 3.1%, respectively; both p< 0.001) and worse health-related QoL on all domains of the KHQ. In multiple logistic regression models adjusted for sociodemographic and clinical variables of uro-gynaecological history, perceived symptoms of mild-to-severe depression were associated with a higher amount of leakage (OR=3.59; 1.04– 12.4), older age (≥ 55 years old vs < 55 years old) (OR=5.82; 1.47– 23.1) and higher BMI (OR=1.13; 1.01– 1.27). In addition, when controlled for all domains of the KHQ, perceived depressive symptoms were associated with the “emotions” domain of the KHQ (OR=1.06; 1.02– 1.09). Perceived anxiety symptoms (independent of age) were related to shorter duration of SUI, low parity, absence of comorbidities and to higher scores on the “personal relationships” and “emotions” domains of the KHQ.Conclusion: Women with SUI have a significantly poorer QoL than their counterparts without SUI. It was determined that one-half of women with SUI had anxiety symptoms, while one-third of women with SUI had depressive symptoms. In addition, this study indicated that QoL was associated with anxiety symptoms in middle-aged women and with depressive symptoms in older women, especially those with a shorter duration of SUI.Keywords: urinary incontinence, anxiety, depression, King’s Health Questionnaire
