Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient

Chia-Eng Wu; Hsiang-Po Huang; Hong-Nerng Ho; Mei-Jou Chen

Stem Cell Research (Feb 2025)

Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient

Chia-Eng Wu,
Hsiang-Po Huang,
Hong-Nerng Ho,
Mei-Jou Chen

Affiliations

Chia-Eng Wu: Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
Hsiang-Po Huang: Graduate Institute of Medical Genomics and Proteomics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
Hong-Nerng Ho: Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan; Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan
Mei-Jou Chen: Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan; Livia Shangyu Wan Chair Professor of Obstetrics and Gynecology, National Taiwan University, Taipei, Taiwan Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author.

Journal volume & issue: Vol. 82
p. 103647

Abstract

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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