Hypoglycemic Interaction Effects of 4 and 6 Weeks Swimming Training and Aloe barbadensis Hydroalcoholic Extract in Streptozotocin Induced Diabetic Rats

Abstract

Background: Exercise and nutrition are basic pillars of taking care and management of diabetes. Objective: Aim of present study was to review the hypoglycemic interaction effects of swimming and Aloe barbadensis in diabetic rats. Methods: 72 diabetic rats selected and divided in 9 groups (1) first week control, (2) fourth week control, (3) sixth week control, (4) 4 weeks Aloe barbadensis, (5) 6 weeks Aloe barbadensis, (6) 4 weeks swimming, (7) 6 weeks swimming, (8) 4 weeks swimming with Aloe barbadensis, (9) 6 weeks swimming with Aloe barbadensis. For review the effect of diabetes induction 24 healthy rats selected and divided in 3 groups (10) first week control, (11) fourth week control and (12) sixth week control. Groups 6 and 8 swam for 4 weeks and rats of groups 7 and 9 swam for 6 weeks, 5 sessions per week and 30 minutes per session also groups 4, 5, 8 and 9 received 100 mg/kg Aloe barbadensis daily. For statistical analysis of data used one-way ANOVA, two-way ANOVA and bonferroni post hoc tests (P≤0.05). Results: Diabetes induction has significant effect on increase of glucose and insulin resistance and reduction of insulin in diabetic rats (P<0.05), swimming training, Aloe barbadensis and combination of swimming and Aloe barbadensis have significant effect on reduction of glucose and insulin resistance (P<0.05) also 6 weeks swimming rather than 4 weeks and 6 weeks Aloe barbadensis rather than 4 weeks have more effect on reduction of glucose and insulin resistance (P<0.05). Conclusion: 4 and 6 weeks swimming and Aloe barbadensis have hypoglycemic interaction effects in diabetic rats.

Keywords

• swimming training
• aloe barbadensis
• diabetes
• glycemic indexes