CHEMICAL ANALYTICAL APPROACHES OF DETERMINATION OF CONTENT OF CHLOROHYDROCARBONS AND THEIR METABOLITES IN BIOLOGICAL MATRIXES

Abstract

Improving of methodical approaches to gas chromatography methodologies of determination, of chlorohydrocarbons — vinyl chloride, 1,2-dichloroethane — and their metabolites — chloroethanol, monochloroacetic acid, and. thiodiglycolic acid. — in biological matrixes (blood and. urine) is reviewed. Metrological characteristics were determined. Content of these chemical compounds and. their metabolites in biological matrixes of workers contacting with chlorohydrocarbons was studied.

Keywords

• 1
• 2-дихлорэтан
• vinyl chloride
• 1
• 2-dichloroethane
• metabolites in biological matrixes
• gas chromatographic method
• liquid-liquid micro extraction
• monochloroacetic acid