Torsion of juvenile granulosa cell ovarian tumor

Abstract

Juvenile granulosa cell tumor (JGCT), which is one of the sex cord-stromal tumors of the ovary, is a rare malignancy of childhood. Juvenile type is a rare form that accounts for 5% of granulosa cell tumors. Isosexual precocious puberty is the most common presentation in prepubertal girls with juvenile granulosa cell tumors. Less frequently, they present with the complaint of a mass in the abdomen.We present an 8-year-old girl with a juvenile granulosa cell tumor who presented with sudden onset of abdominal pain and enlargement of the abdomen. She underwent exploratory laparotomy with right salpingo-oophorectomy and a complete mass resection was performed. Pathologic staging of the mass, which was diagnosed as juvenile granulosa cell tumor of the ovary, was determined as pT1c3, and our patient received four cycles of chemotherapy.

Keywords

• Juvenile granulosa cell tumor
• Alpha-inhibin
• Immunohistochemistry
• Ovarian sex cord-stromal tumors