Histopathology of the skin in rheumatic diseases

M.S. Chimenti; A. Di Stefani; P. Conigliaro; A. Saggini; S. Urbani; A. Giunta; M. Esposito; L. Bianchi; K. Peris; R. Perricone

doi:10.4081/reumatismo.2018.1049

Reumatismo (Oct 2018)

Histopathology of the skin in rheumatic diseases

M.S. Chimenti,
A. Di Stefani,
P. Conigliaro,
A. Saggini,
S. Urbani,
A. Giunta,
M. Esposito,
L. Bianchi,
K. Peris,
R. Perricone

Affiliations

M.S. Chimenti: Rheumatology, Allergology and Clinical Immunology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
A. Di Stefani: Institute of Dermatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome
P. Conigliaro: Rheumatology, Allergology and Clinical Immunology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
A. Saggini: Department of Biomedicine and Prevention, Anatomic Pathology, University of Tor Vergata, Rome
S. Urbani: Rheumatology, Allergology and Clinical Immunology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
A. Giunta: Dermatology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
M. Esposito: Dermatology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
L. Bianchi: Dermatology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome
K. Peris: Institute of Dermatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome
R. Perricone: Rheumatology, Allergology and Clinical Immunology, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome

DOI: https://doi.org/10.4081/reumatismo.2018.1049
Journal volume & issue: Vol. 70, no. 3

Abstract

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Rheumatological systemic autoimmune diseases, such as connective tissue diseases, rheumatoid arthritis or spondyloarthritis, are characterized by the presence of joint involvement associated with extra-articular manifestations. Among them, cutaneous diseases are often the most relevant and representative clinical manifestation, as in psoriatic arthritis, scleroderma or systemic lupus erythematosus. In this context, it is useful for rheumatologists to understand better skin diseases and their histopathological features. Evaluation of skin biopsy specimens can be helpful not only to confirm the diagnosis in both classic and clinically atypical variants, but also to improve further our knowledge of the pathogenetic mechanisms and the close link between skin and articular diseases. In this review, we discuss the clinical features, diagnostic evaluation and the histopathological features of skin manifestation of the most relevant rheumatological autoimmune diseases.

Published in Reumatismo

ISSN: 0048-7449 (Print); 2240-2683 (Online)
Publisher: PAGEPress Publications
Country of publisher: Italy
LCC subjects: Medicine: Internal medicine
Website: http://www.reumatismo.org

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Abstract

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