Platelet indices in evaluation of patients with recurrent pregnancy loss

Abstract

Objective: To explore the change of platelet indices namely plateletcrit, platelet distribution width and mean platelet volume among patients with recurrent pregnancy loss (RPL).Methods: The medical records of 45 women with a history of RPL and 45 women who gave birth without RPL were reviewed retrospectively from three governmental hospitals in Yemen. The personal, obstetric and complete blood count reports were analyzed.Results: Platelets’ count and indices were significantly higher among RPL patients when compared to the control and the receiver operating characteristic curve for each platelet index showed significant area under the curve, with higher area for plateletcrit followed by platelet distribution width and then mean platelet volume. While the multiple logistic regression analysis for all platelets indices revealed that the platelet distribution width was the significant predictor for RPL in this study.Conclusions: The use of platelet indices may help gynecologists in predicting high risk pregnancy (pregnancy loss) in the low resources areas in Yemen.

Keywords

• Pregnancy loss
• Platelets
• Platelet distribution width
• Mean platelet volume
• Plateletcrit