Capsule robots for the monitoring, diagnosis, and treatment of intestinal diseases

Xiangyu Wei; Peipei Xi; Minjie Chen; Ya Wen; Hao Wu; Li Wang; Yujuan Zhu; Yile Ren; Zhifeng Gu

Materials Today Bio (Dec 2024)

Capsule robots for the monitoring, diagnosis, and treatment of intestinal diseases

Xiangyu Wei,
Peipei Xi,
Minjie Chen,
Ya Wen,
Hao Wu,
Li Wang,
Yujuan Zhu,
Yile Ren,
Zhifeng Gu

Affiliations

Xiangyu Wei: Department of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China; Department of Rheumatology, Affiliated Municipal Hospital of Xuzhou Medical University, Xuzhou, 221100, China; Suzhou Medical College, Soochow University, Suzhou, 215123, China
Peipei Xi: Department of Emergency, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China; Suzhou Medical College, Soochow University, Suzhou, 215123, China
Minjie Chen: Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China
Ya Wen: Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China
Hao Wu: Department of Otolaryngology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China
Li Wang: Institutes of Biomedical Sciences and the Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai, 200032, China
Yujuan Zhu: Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China; Corresponding author.
Yile Ren: Department of Rheumatology, Affiliated Municipal Hospital of Xuzhou Medical University, Xuzhou, 221100, China; Corresponding author.
Zhifeng Gu: Department of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China; Corresponding author.

Journal volume & issue: Vol. 29
p. 101294

Abstract

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Current evidence suggests that the intestine as the new frontier for human health directly impacts both our physical and mental health. Therefore, it is highly desirable to develop the intelligent tool for the enhanced diagnosis and treatment of intestinal diseases. During the past 20 years, capsule robots have opened new avenues for research and clinical applications, potentially revolutionizing human health monitor, disease diagnosis and treatment. In this review, we summarize the research progress of edible multifunctional capsule robots in intestinal diseases. To begin, we introduce the correlation between the intestinal microbiome, intestinal gas and human diseases. After that, we focus on the technical structure of edible multifunctional robots. Subsequently, the biomedical applications in the monitoring, diagnosis and treatment of intestinal diseases are discussed in detail. Last but not least, the main challenges of multifunctional capsule robots during the development process are summarized, followed by a vision for future development opportunities.

Published in Materials Today Bio

ISSN: 2590-0064 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/materials-today-bio

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