Assessment of Vitamin D Level and Its Relation to Glycemic Control Among Patients with Type 2 Diabetes Mellitus in Khartoum State

Abstract

Abstract Background: Type II diabetes is a chronic hyperglycemic disorder.Vitamin D appears to be associated with chronic disease prevention and modulation of immunity. This study was designed to associate vitamin D levels with glycemic control among type 2 diabetes mellitus in Khartoum state. Methods: This was a prospective case-control study conducted between June and November 2021 in Khartoum, Sudan. In total, 80 individuals were included in the study, of which 40 had type 2 diabetes mellitus, while the other 40 were normal, apparently healthy individuals. Vitamin D was measured by ELISA. Results: SPSS was used for statistical analysis. Results showed that 20% of case group (patients with diabetes mellitus) had suboptimal vitamin D levels, whereas 80% had vitamin D deficiency. Vitamin D levels were significantly decreased among the case group when compared to the control group (P-value = 0.00). The glycated hemoglobin was negatively correlated with vitamin D level (P-value = 0.017, R = –0.376). Conclusion: In this study, a significant decrease in vitamin D was seen among people with type 2 DM. There was a weak negative correlation between hemoglobin A1C and vitamin D level, and no significant difference in Vitamin D levels among gender and different types of treatment.

Keywords

• diabetes mellitus, vitamin d, glycemic control