Qualification and quantification of plasma cell-free DNA after long-term storage conditions in patients with benign prostatic hyperplasia (BPH): a pilot study

Bozkurt Aliseydi; Gürbüzel Mehmet; Sayar Ilyas; Baydeniz Soner; Arslan Yusuf Kemal

doi:10.1515/labmed-2022-0044

Journal of Laboratory Medicine (Dec 2022)

Qualification and quantification of plasma cell-free DNA after long-term storage conditions in patients with benign prostatic hyperplasia (BPH): a pilot study

Bozkurt Aliseydi,
Gürbüzel Mehmet,
Sayar Ilyas,
Baydeniz Soner,
Arslan Yusuf Kemal

Affiliations

Bozkurt Aliseydi: Department of Urology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Türkiye
Gürbüzel Mehmet: Department of Medical Biology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Türkiye
Sayar Ilyas: Department of Pathology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Türkiye
Baydeniz Soner: Department of Biology, Graduate School of Natural and Applied Sciences, Erzincan Binali Yıldırım University, Erzincan, Türkiye
Arslan Yusuf Kemal: Department of Biostatistics, Medical Faculty, Çukurova University, Adana, Türkiye

DOI: https://doi.org/10.1515/labmed-2022-0044
Journal volume & issue: Vol. 46, no. 6
pp. 383 – 389

Abstract

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Free DNA is used as a cancer biomarker due to its low cost, high applicability, and fast, reliable results compared to invasive methods. This study aimed to evaluate the quantification of plasma-free DNA after long-term storage conditions and perform qualification through single nucleotide polymorphism (SNP) screening based on this DNA.

Published in Journal of Laboratory Medicine

ISSN: 2567-9430 (Print); 2567-9449 (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Medicine: Medicine (General): Medical technology
Website: https://www.degruyter.com/view/journals/labm/labm-overview.xml

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