Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome

M.M. Gridina; E.M. Shitik; N.A. Lemskaya; J.M. Minina; I.V. Grishchenko; A.A. Dolskiy; A.R. Shorina; Y.V. Maksimova; D.V. Yudkin

Stem Cell Research (Dec 2021)

Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome

M.M. Gridina,
E.M. Shitik,
N.A. Lemskaya,
J.M. Minina,
I.V. Grishchenko,
A.A. Dolskiy,
A.R. Shorina,
Y.V. Maksimova,
D.V. Yudkin

Affiliations

M.M. Gridina: Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia; Corresponding author.
E.M. Shitik: State Research Center of Virology and Biotechnology “Vector”, Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB “Vector”, Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia
N.A. Lemskaya: Institute of Molecular and Cellular Biology, SB RAS, Novosibirsk, Russia
J.M. Minina: Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
I.V. Grishchenko: State Research Center of Virology and Biotechnology “Vector”, Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB “Vector”, Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia
A.A. Dolskiy: State Research Center of Virology and Biotechnology “Vector”, Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB “Vector”, Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia
A.R. Shorina: SBIH Novosibirsk Municipal Clinical Hospital №1, Novosibirsk, Russia
Y.V. Maksimova: SBIH Novosibirsk Municipal Clinical Hospital №1, Novosibirsk, Russia; Novosibirsk State Medical University, Novosibirsk, Russia
D.V. Yudkin: State Research Center of Virology and Biotechnology “Vector”, Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB “Vector”, Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia

Journal volume & issue: Vol. 57
p. 102615

Abstract

Read online

Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

About the journal