eNeurologicalSci (Jun 2016)

Non-motor signs in patients with Parkinson's disease at the University Hospital of Point “G”, Mali

  • Boubacar Maïga,
  • Aïssata Koné,
  • Guida Landouré,
  • Toumany Coulibaly,
  • Modibo Sangaré,
  • Kekouta Dembélé,
  • Marième Soda Diop,
  • Lassana Cissé,
  • Sami Mohamed Lemine Dadah,
  • Mamadou Konaté,
  • Catherine Coulibaly,
  • Adama Seydou Sissoko,
  • Thomas Coulibaly,
  • Mamadou Karambé,
  • Cheick Oumar Guinto,
  • M. Moustapha Ndiaye,
  • Mouhamadou Mansour Ndiaye,
  • Moussa Traoré

DOI
https://doi.org/10.1016/j.ensci.2016.02.001
Journal volume & issue
Vol. 3, no. C
pp. 35 – 36

Abstract

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Introduction: Despite significant progress in the field of scientific research on Parkinson's disease (PD), the prevalence and pathophysiology of its non-motor signs remains less understood than the classic motor signs of bradykinesia, rigidity, tremor and postural instability. Data covering this topic are rare in Africa, and almost non-existent in sub-Saharan Africa. Thus, this study aims to highlight the frequency of certain non-motor signs in PD patients followed in the Department of Neurology of the University Hospital Point “G”, Bamako, Mali. Methodology: This is a retrospective and descriptive study from January 2012 to November 2013. We identified records of patients with dopamine-responsive idiopathic Parkinson's disease, and quantified associated non-motor symptoms. Data were analyzed with Epi-Info 2000 version 3.5.5. Result: During this period we reviewed 60 patient charts of which 68.3% were men. The average age of patients was 66.51 ranging from 25 to 94 years. Non-motor symptoms were present in 90% of cases, including sensitive disorders in 76.7%, dysautonomia in 73.3%, and psycho-behavioral disorders, including sleep disorders, in 81.7%. Conclusion: At the end of this study, we observed an important place for non-motor signs in the clinical manifestation of PD patients in general.

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