Intestinal microbiome composition and its relation to joint pain and inflammation

Cindy G. Boer; Djawad Radjabzadeh; Carolina Medina-Gomez; Sanzhima Garmaeva; Dieuwke Schiphof; Pascal Arp; Thomas Koet; Alexander Kurilshikov; Jingyuan Fu; M. Arfan Ikram; Sita Bierma-Zeinstra; André G. Uitterlinden; Robert Kraaij; Alexandra Zhernakova; Joyce B. J. van Meurs

doi:10.1038/s41467-019-12873-4

Nature Communications (Oct 2019)

Intestinal microbiome composition and its relation to joint pain and inflammation

Cindy G. Boer,
Djawad Radjabzadeh,
Carolina Medina-Gomez,
Sanzhima Garmaeva,
Dieuwke Schiphof,
Pascal Arp,
Thomas Koet,
Alexander Kurilshikov,
Jingyuan Fu,
M. Arfan Ikram,
Sita Bierma-Zeinstra,
André G. Uitterlinden,
Robert Kraaij,
Alexandra Zhernakova,
Joyce B. J. van Meurs

Affiliations

Cindy G. Boer: Department of Internal Medicine, Erasmus MC, University Medical Center
Djawad Radjabzadeh: Department of Internal Medicine, Erasmus MC, University Medical Center
Carolina Medina-Gomez: Department of Internal Medicine, Erasmus MC, University Medical Center
Sanzhima Garmaeva: Department of Genetics, University Medical Center Groningen, University of Groningen
Dieuwke Schiphof: Department of General Practice, Erasmus MC, University Medical Center
Pascal Arp: Department of Internal Medicine, Erasmus MC, University Medical Center
Thomas Koet: Department of Internal Medicine, Erasmus MC, University Medical Center
Alexander Kurilshikov: Department of Genetics, University Medical Center Groningen, University of Groningen
Jingyuan Fu: Department of Genetics, University Medical Center Groningen, University of Groningen
M. Arfan Ikram: Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam
Sita Bierma-Zeinstra: Department of General Practice, Erasmus MC, University Medical Center
André G. Uitterlinden: Department of Internal Medicine, Erasmus MC, University Medical Center
Robert Kraaij: Department of Internal Medicine, Erasmus MC, University Medical Center
Alexandra Zhernakova: Department of Genetics, University Medical Center Groningen, University of Groningen
Joyce B. J. van Meurs: Department of Internal Medicine, Erasmus MC, University Medical Center

DOI: https://doi.org/10.1038/s41467-019-12873-4
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 9

Abstract

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Alterations to the microbiome are now associated with various diseases. Here the authors analyze microbiomes from a large population based cohort and show positive correlations between abundance of Streptococcus spp. and osteoarthritis-related knee pain.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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