Probable sporadic Creutzfeldt–Jakob disease mimicking focal epilepsy

Pei-Shan Hsiao; Yuan-Ming Lee; Fu-Sin Chu; Chao-Lin Lee; Fang-Chun Liu; Ping-Huang Tsai

Epilepsy and Behavior Case Reports (Jan 2019)

Probable sporadic Creutzfeldt–Jakob disease mimicking focal epilepsy

Pei-Shan Hsiao,
Yuan-Ming Lee,
Fu-Sin Chu,
Chao-Lin Lee,
Fang-Chun Liu,
Ping-Huang Tsai

Affiliations

Pei-Shan Hsiao: Department of Laboratory Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan
Yuan-Ming Lee: Department of Laboratory Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan
Fu-Sin Chu: Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Center for Dementia Care and Evolution, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan
Chao-Lin Lee: Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Center for Dementia Care and Evolution, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan
Fang-Chun Liu: Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Center for Dementia Care and Evolution, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan
Ping-Huang Tsai: Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Center for Dementia Care and Evolution, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan; Department of Neurology, School of Medicine, National Yang-Ming University, No.155, Sec.2, Linong Street, Taipei 112, Taiwan; Corresponding author at: Division of Neurology, Department of Internal Medicine, National Yang-Ming University Hospital, No.169, Siaoshe Rd., Yilan City, Yilan County 26058, Taiwan.

Journal volume & issue: Vol. 11
pp. 77 – 80

Abstract

Read online

Creutzfeldt–Jakob disease (CJD) presents with seizures as an early symptom in only approximately 3% of cases. These seizures often present as nonconvulsive status epilepticus (NCSE) or epilepsia partialis continua (EPC). Here, we describe a case of probable sporadic CJD (sCJD) in an 83-year-old man whose manifest an unusual presentation of left-hand tonic seizures without evolution to EPC, as well as brain MRI findings interpreted as peri-ictal changes, which led to an initial misdiagnosis of focal epilepsy. Keywords: Creutzfeldt–Jakob disease, Seizure, EEG, MRI

Published in Epilepsy and Behavior Case Reports

ISSN: 2213-3232 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.journals.elsevier.com/epilepsy-and-behavior-case-reports/

About the journal