Nature Communications (Jan 2023)

Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells

  • Helena G. Asenjo,
  • María Alcazar-Fabra,
  • Mencía Espinosa-Martínez,
  • Lourdes Lopez-Onieva,
  • Amador Gallardo,
  • Emilia Dimitrova,
  • Angelika Feldmann,
  • Tomas Pachano,
  • Jordi Martorell-Marugán,
  • Pedro Carmona-Sáez,
  • Antonio Sanchez-Pozo,
  • Álvaro Rada-Iglesias,
  • Robert J. Klose,
  • David Landeira

DOI
https://doi.org/10.1038/s41467-023-35859-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

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Changes in Polycomb repression during interphase transition modulate the ability of pluripotent cells to enter cell differentiation.