Application of Flow Cytometry in the Diagnosis of Bovine Epidemic Disease

Zhilin Liu; Yuliang Zhang; Donghui Zhao; Yunjiao Chen; Qinglei Meng; Xin Zhang; Zelin Jia; Jiayu Cui; Xueli Wang

doi:10.3390/v15061378

Viruses (Jun 2023)

Application of Flow Cytometry in the Diagnosis of Bovine Epidemic Disease

Zhilin Liu,
Yuliang Zhang,
Donghui Zhao,
Yunjiao Chen,
Qinglei Meng,
Xin Zhang,
Zelin Jia,
Jiayu Cui,
Xueli Wang

Affiliations

Zhilin Liu: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Yuliang Zhang: Tongliao City Animal Quarantine Technical Service Centre, Tongliao 028000, China
Donghui Zhao: Tongliao City Animal Quarantine Technical Service Centre, Tongliao 028000, China
Yunjiao Chen: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Qinglei Meng: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Xin Zhang: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Zelin Jia: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Jiayu Cui: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China
Xueli Wang: College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China

DOI: https://doi.org/10.3390/v15061378
Journal volume & issue: Vol. 15, no. 6
p. 1378

Abstract

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As science and technology continue to advance, the use of flow cytometry is becoming more widespread. It can provide important information about cells in the body by detecting and analysing them, thereby providing a reliable basis for disease diagnosis. In the diagnosis of bovine epidemic diseases, flow cytometry can be used to detect bovine viral diarrhoea, bovine leukaemia, bovine brucellosis, bovine tuberculosis, and other diseases. This paper describes the structure of a flow cytometer (liquid flow system, optical detection system, data storage and analysis system) and its working principles for rapid quantitative analysis and sorting of single cells or biological particles. Additionally, the research progress of flow cytometry in the diagnosis of bovine epidemic diseases was reviewed in order to provide a reference for future research and application of flow cytometry in the diagnosis of bovine epidemic diseases.

Published in Viruses

ISSN: 1999-4915 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.mdpi.com/journal/viruses

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