Journal of Allergy and Clinical Immunology: Global (May 2024)

Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station

  • Satish K. Mehta, PhD,
  • Rahul Suresh, MD,
  • Keith Brandt, MD,
  • Douglass M. Diak, PhD,
  • Scott M. Smith, PhD,
  • Sara R. Zwart, PhD,
  • Grace Douglas, PhD,
  • Mayra Nelman-Gonzalez, BA,
  • Simon Clemett, PhD,
  • Tyson Brunstetter, OD, PhD,
  • Brian E. Crucian, PhD

Journal volume & issue
Vol. 3, no. 2
p. 100244

Abstract

Read online

A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed.

Keywords