Can Sagittal Sinus Flow Augmentation Aid in Controlling Intracranial Hypertension? Physiological Rationale and Pilot Feasibility Assessment in a Porcine Model

Abstract

In a porcine model of intracranial hypertension generated by production of intracranial hemorrhage, the sagittal sinus was catheterized and periodic withdrawal of blood was performed. ICP reliably reduced with sinus blood aspiration in both pilot subjects. Our preliminary results suggest a potential role of targeted sagittal sinus aspiration in aiding control of increased ICP conditions, especially when refractory.