Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

Abstract

Objective To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

Keywords

• severe preeclampsia
• uric acid
• renal function
• immediate delivery
• prolongation