A rare concurrence of acute tubular necrosis and chronic glomerular sclerosis in a patient with wasp stings
Jian-hui Zhang,
Jing Zou,
Dan-dan Ruan,
Qian Chen,
Min Wu,
Hong-ping Yu,
Qiu-yan Wu,
Fan Lin,
Jie-wei Luo,
Li Zhang
Affiliations
Jian-hui Zhang
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Jing Zou
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Dan-dan Ruan
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Qian Chen
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Min Wu
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Hong-ping Yu
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Qiu-yan Wu
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China
Fan Lin
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China; Department of Geriatric Medicine, Fujian Provincial Center for Geriatrics, Fujian Provincial Hospital, Fuzhou, China; Corresponding author. Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, no.134 East Street, Fuzhou, 350001, China.
Jie-wei Luo
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China; Department of Traditional Chinese Medicine, Fujian Provincial Hospital, Fuzhou, China; Corresponding author. Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, no.134 East Street, Fuzhou, 350001, China.
Li Zhang
Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China; Department of Nephrology, Fujian Provincial Hospital, Fuzhou, China; Corresponding author. Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, no.134 East Street, Fuzhou, 350001, China.
Wasp venom injections from wasp stings can damage several organs, most commonly the kidneys. Despite literature evidence, wasp sting-induced acute kidney injury (AKI) is rare and involves complex pathophysiological processes. While acute tubular necrosis (ATN) is the most prevalent histological result of wasp sting-induced AKI, uncommon combinations of chronic renal lesions have been described, alerting us to the patient's underlying illness. We report a 55-year-old hypertensive patient with unknown renal function who got AKI following multiple wasp stings. His renal function had not improved after continuous hemodialysis and plasma exchange; therefore, a kidney biopsy was performed. The pathology revealed that in addition to ATN, his kidney's distinguishing feature was a mix of chronic interstitial renal disease and chronic glomerulosclerosis. We think that his current renal pathological results were caused by hypertension in addition to wasp venom.
