Use of nimesulide in rheumatology

Abstract

The paper gives data on the basic mechanisms of action of nimesulide, a nonsteroidal anti-inflammatory drug that has anti-inflammatory, analgesic, and antipyretic activities in a broad spectrum of morbid states. It shows the rate of effect occurrence after administration of different nimesulide formulations in gouty arthritis and considers the aspects of its safety and tolerability in rheumatic diseases.