Prereplication complex proteins get caught moonlighting

Abstract

In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans. This Primer explores the implications of a PLOS Biology study that reports a novel function for proteins of the DNA pre-replication complex in promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.