Microwave Assisted Synthesis of N-Benzylenaminones Catalyzed by Chloroacetic Acid

Abstract

Benzylaminoalkenones and benzylaminoalkenoates 3 were synthesized from reaction of benzylamine with corresponding 1,3-diketones and 1,3-ketoesters in the presence of catalytic amount of chloroacetic acid under microwave radiation. This method offers several advantages including high yield of products, recyclable of the catalyst and easy experimental work-up procedure.

Keywords

• microwave synthesis ; 1 ; 3-diketones ; 3-ketoesters ; benzylamine ; chloroacetic acid