Frontiers in Cellular Neuroscience (Jan 2023)

The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

  • Weiming Lin,
  • Feng Gao,
  • Xia Wang,
  • Nianhong Qin,
  • Xianxiong Chen,
  • Kin Yip Tam,
  • Chengfei Zhang,
  • Chengfei Zhang,
  • Mingxia Zhang,
  • Ou Sha

DOI
https://doi.org/10.3389/fncel.2022.1006977
Journal volume & issue
Vol. 16

Abstract

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Coronavirus disease 2019 (COVID-19) was reported to be associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and patients present mostly with respiratory symptoms. There have been an increasing number of reports on oral manifestations, and some of these signs are informative in terms of identifying SARS-CoV-2 infection. The goal of present study was to review and synthesize the clinical characteristics and underlying mechanisms of COVID-19 oral manifestations, as well as to evaluate the factors influencing SARS-CoV-2 infectivity, in order to conduct further in-depth investigations and help clinicians diagnose COVID-19 patients exhibiting oral symptoms.

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