Journal of Pharmacy and Bioallied Sciences (Jan 2016)

Role of plasma-rich fibrin in oral surgery

  • K Retna Kumar,
  • K Genmorgan,
  • S M Abdul Rahman,
  • M Alaguvel Rajan,
  • T Arul Kumar,
  • V Srinivas Prasad

DOI
https://doi.org/10.4103/0975-7406.191963
Journal volume & issue
Vol. 8, no. 5
pp. 36 – 38

Abstract

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Platelet-rich fibrin (PRF) is a fibrin meshwork, in which platelet cytokines, growth factors, and cells are entrapped and discharged after a period and can serve as a resorbable film. PRF is the next generation of platelet concentrates equipped to improve arrangement without biochemical blood handling; PRF is an evolution of the fibrin adhesive, which is widely used in the oral surgery. The guidelines of this innovation depend on concentrating platelets and growth factors in a plasma medium, and initiating them in a fibrin gel, keeping in mind the end goal to enhance the healing of wounds. Maxillary bone loss requires numerous regenerative techniques: as a supplement to the procedures of tissue regeneration, a platelet concentrate called PRF was tested for the 1st time in France by Dr. Choukroun. This article enriches the benefits and role of plasma-rich fibrin in oral surgery. Platelet-concentrate fibrin is an evolution of the fibrin glue, which is widely used in the oral surgery.

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