BMC Oral Health (Jan 2024)

The current applications of nano and biomaterials in drug delivery of dental implant

  • Lotfollah Kamali Hakim,
  • Amir Yari,
  • Nariman Nikparto,
  • Saeed Hasani Mehraban,
  • Sahar Cheperli,
  • Amirali Asadi,
  • Amirmohammad Arabi Darehdor,
  • Sayna Nezaminia,
  • Dorara Dortaj,
  • Yasin Nazari,
  • Mohamad Dehghan,
  • Pardis Hojjat,
  • Mahsa Mohajeri,
  • Mohammad Saleh Hasani Jebelli

DOI
https://doi.org/10.1186/s12903-024-03911-9
Journal volume & issue
Vol. 24, no. 1
pp. 1 – 15

Abstract

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Abstract Background and aim Dental implantology has revolutionized oral rehabilitation, offering a sophisticated solution for restoring missing teeth. Despite advancements, issues like infection, inflammation, and osseointegration persist. Nano and biomaterials, with their unique properties, present promising opportunities for enhancing dental implant therapies by improving drug delivery systems. This review discussed the current applications of nano and biomaterials in drug delivery for dental implants. Method A literature review examined recent studies and advancements in nano and biomaterials for drug delivery in dental implantology. Various materials, including nanoparticles, biocompatible polymers, and bioactive coatings, were reviewed for their efficacy in controlled drug release, antimicrobial properties, and promotion of osseointegration. Results Nano and biomaterials exhibit considerable potential in improving drug delivery for dental implants. Nanostructured drug carriers demonstrate enhanced therapeutic efficacy, sustained release profiles, and improved biocompatibility. Furthermore, bioactive coatings contribute to better osseointegration and reduced risks of infections. Conclusion Integrating current nano and biomaterials in drug delivery for dental implants holds promise for advancing clinical outcomes. Enhanced drug delivery systems can mitigate complications associated with dental implant procedures, offering improved infection control, reduced inflammation, and optimized osseointegration.

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