Probable recurrence of cardiac sarcoidosis in a transplanted heart
Matthew Seplowe, DO,
Shazli Khan, MD,
Lakshmisree Vemulakonda, MD,
Fouzia Shakil, MD,
Liana Michaud, DO,
Chhaya Aggarwal-Gupta, MD,
Gregg Lanier, MD,
Avi Levine, MD,
Suguru Ohira, MD, PhD,
David Spielvogel, MD,
Alan Gass, MD,
Stephen Pan, MD, MS
Affiliations
Matthew Seplowe, DO
Department of Hospital Medicine, Mount Sinai Morningside, New York, New York
Shazli Khan, MD
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Lakshmisree Vemulakonda, MD
Department of Pathology, Westchester Medical Center, New York Medical College, Valhalla, New York
Fouzia Shakil, MD
Department of Pathology, Westchester Medical Center, New York Medical College, Valhalla, New York
Liana Michaud, DO
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Chhaya Aggarwal-Gupta, MD
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Gregg Lanier, MD
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Avi Levine, MD
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Suguru Ohira, MD, PhD
Department of Cardiothoracic Surgery, Westchester Medical Center, New York Medical College, Valhalla, New York
David Spielvogel, MD
Department of Cardiothoracic Surgery, Westchester Medical Center, New York Medical College, Valhalla, New York
Alan Gass, MD
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York
Stephen Pan, MD, MS
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York; Corresponding author: Stephen Pan, MD, MS, Department of Cardiology, Westchester Medical Center, New York Medical College, 100 Woods Road, Macy 135, Valhalla, NY 10595.
Recurrence of cardiac sarcoidosis (CS) in post-transplant patients presents a rare but potentially life-threatening form of graft dysfunction and poses challenges due to varying clinical presentations, limited diagnostic modalities, and treatments based on anecdotal evidence. We discuss the case of a 46-year-old woman with CS, who developed cardiogenic shock necessitating orthotopic heart transplant. She subsequently developed likely recurrent CS in the transplanted heart. We discuss the rarity of this scenario as well as diagnostic modalities and management principles to consider.
