RITUXIMAB IN PEDIATRIC RHEUMATOLOGY

Voprosy Sovremennoj Pediatrii. 2010;9(3):54-62

 

Journal Homepage

Journal Title: Voprosy Sovremennoj Pediatrii

ISSN: 1682-5527 (Print); 1682-5535 (Online)

Publisher: "Paediatrician" Publishers LLC

Society/Institution: The Union of Pediatricians of Russia

LCC Subject Category: Medicine: Pediatrics

Country of publisher: Russian Federation

Language of fulltext: Russian, English

Full-text formats available: PDF

 

AUTHORS

E.I. Alexeeva (Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow)
R.V. Denisova (Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow)
S.I. Valieva (Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow)
T.M. Bzarova (Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow)
A.O. Lisitsyn (Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow)

EDITORIAL INFORMATION

Blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

<p><em>The article presents literature review on the role of B-lymphocytes in pathogenesis of rheumatologic diseases and on the administration of chimeric anti-CD20 monoclonal antibodies — rituximab — for treatment of systemic lupus erythematosus, systemic vasculitis, juvenile dermatomyositis, and juvenile arthritis in children. Results of studies showed that rituximab has good tolerability, efficacy and safety in children’s rheumatologic practice.</em><strong><em></em></strong></p><p><strong><em>Key words: children, B-lymphocytes, rituximab, treatment, depletion.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em>Voprosy sovremennoi pediatrii — </em></em>Current Pediatrics. – 2010;9(3):<em>54-62</em>)</em></span></p>