Diabetology & Metabolic Syndrome (Dec 2010)

Meeting Report: 3<sup>rd </sup>International Workshop on Insulin & Cancer Heidelberg, Germany, October 30-31, 2010

  • Chantelau Ernst,
  • Mayer Doris

DOI
https://doi.org/10.1186/1758-5996-2-73
Journal volume & issue
Vol. 2, no. 1
p. 73

Abstract

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Abstract The 3rd International Workshop on Insulin & Cancer was held on October 30-31, 2010 at the German Cancer Research Centre in Heidelberg/Germany. The topics followed-up the discussions of the previous workshops: possible differences in mitogenicity between natural insulin and genetically engineered insulin derivatives (insulin analogues), as shown by laboratory studies and epidemiologic studies alike; molecular studies on the links between metabolic and mitogenic effects of insulin, and of hyperinsulinaemia in particular; epidemiologic evidence of interferences between insulin and other hormones, particularly sex hormones, and obesity-associated cancer; the involvement of inflammatory cytokines produced by fat tissue in obesity-associated cancer; aspects of drug-design (binding drugs to albumin) and, last but not least, detection and investigation of circulating cancer cells.