Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation

Josh P. Prince; Jani R. Bolla; Gemma L. M. Fisher; Jarno Mäkelä; Marjorie Fournier; Carol V. Robinson; Lidia K. Arciszewska; David J. Sherratt

doi:10.1038/s41467-021-27107-9

Nature Communications (Nov 2021)

Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation

Josh P. Prince,
Jani R. Bolla,
Gemma L. M. Fisher,
Jarno Mäkelä,
Marjorie Fournier,
Carol V. Robinson,
Lidia K. Arciszewska,
David J. Sherratt

Affiliations

Josh P. Prince: Department of Biochemistry, University of Oxford
Jani R. Bolla: Physical and Theoretical Chemistry Laboratory, University of Oxford
Gemma L. M. Fisher: Department of Biochemistry, University of Oxford
Jarno Mäkelä: Department of Biochemistry, University of Oxford
Marjorie Fournier: Department of Biochemistry, University of Oxford
Carol V. Robinson: Physical and Theoretical Chemistry Laboratory, University of Oxford
Lidia K. Arciszewska: Department of Biochemistry, University of Oxford
David J. Sherratt: Department of Biochemistry, University of Oxford

DOI: https://doi.org/10.1038/s41467-021-27107-9
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 12

Abstract

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E. coli MukBEF is an SMC complex that plays key roles in chromosome organization-segregation. Here the authors show that the interaction between MukBEF and the Acyl Carrier Protein (AcpP) is essential for MukBEF activity in vitro (ATPase) and in vivo.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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