Histopathological alterations in brains of rabies infected buffaloes and cattle

Abstract

The quantitative study of histopathological alterations in the nervous tissues of 47 rabid buffaloes and 23 rabid cattle, it was found that there were certain similarities and significant differences in the histopathological alterations in various nervous tissues of these two species - that were often over looked. Whereas there was significant detection of Negri bodies in cerebellum both in cattle (91.3%) as well as in buffaloes (85.1%), however, in case of cerebrum, significant presence of Negri bodies was found only in buffaloes (65.95%) than in cattle (13.0%). Thus, in case of non-availability of cerebellum, Negri body detection could be attempted only in buffalo while it would not be reliable approach in cattle. However, reactive inflammatory response was more consistently present in brainstem than in cerebrum and cerebellum of rabid buffaloes and cattle. Similarly, malacia was more consistent finding in buffaloes (51.6%) than in cattle (26.08%).

Keywords

• Rabies, Buffalo, Cattle, Histopathology