Nature Communications (Jan 2023)

Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme

  • Wenhui Gao,
  • Jiuyang He,
  • Lei Chen,
  • Xiangqin Meng,
  • Yana Ma,
  • Liangliang Cheng,
  • Kangsheng Tu,
  • Xingfa Gao,
  • Cui Liu,
  • Mingzhen Zhang,
  • Kelong Fan,
  • Dai-Wen Pang,
  • Xiyun Yan

DOI
https://doi.org/10.1038/s41467-023-35828-2
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

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Superoxide dismutase (SOD) nanozymes show mitigating effect on oxidative stress-related diseases, but are limited by their modest activity. Here, the authors report a carbon dot SOD nanozyme with catalytic activity matching natural enzymes and unveil its catalytic mechanism.