Two pregnancies during a nine year period of amenorrhea – a rare presentation of Cushing’s disease

Abstract

We describe a young lady with poorly controlled diabetes and prolonged period of amenorrhoea who had two children during that period. Further evaluation confirmed Cushing’s disease and control of hypercortisolaemia with medical therapy improved her symptoms. She underwent transsphenoidal surgery and histology revealed a “pituitary adenoma”. Though pregnancy is uncommon in Cushing's syndrome, this case reports the rare possibility of pregnancy in Cushing’s syndrome even without treatment and unusually during a very long period of amenorrhoea.DOI: http://dx.doi.org/10.4038/sjdem.v3i1.5498 Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2013; 3: 25-28

Keywords

• cushing’s syndrome
• amenorrhoea
• pregnancy