The Use of Formula Derived Glomerular Filtration Rate in Children: a Review

Abstract

Summary: Facilities for investigating renal disorders in children in the developing world are still inadequate. Even when some are available as in the case of creatinine clearance determination, there is still the challenge of accurate urine collection. The newer and easier isotopic methods are unavailable, expensive and pose ethical dilemma. In view of the foregoing and after a critical analysis of its merits and demerits, the formula based glomerular filtration rate (GFR) using height/creatinine formula proposed by Schwartz et al, is recommended.