Nature Communications (Aug 2021)

A microRNA panel compared to environmental and polygenic scores for colorectal cancer risk prediction

  • Janhavi R. Raut,
  • Ben Schöttker,
  • Bernd Holleczek,
  • Feng Guo,
  • Megha Bhardwaj,
  • Kaya Miah,
  • Petra Schrotz-King,
  • Hermann Brenner

DOI
https://doi.org/10.1038/s41467-021-25067-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Appropriate risk models could facilitate risk stratification for colorectal cancer (CRC) screening. Here, the authors propose a blood-based microRNA signature observed to have altered expression in pre-diagnostic samples, which might be useful to identify high-risk populations for colorectal cancer screening.