Клиническая микробиология и антимикробная химиотерапия (Mar 2020)

The reasons why Klebsiella pneumoniae becomes a leading opportunistic pathogen

  • Chebotar I.V.,
  • Bocharova Yu.A.,
  • Podoprigora I.V.,
  • Shagin D.A.

DOI
https://doi.org/10.36488/cmac.2020.1.4-19
Journal volume & issue
Vol. 22, no. 1
pp. 4 – 19

Abstract

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This review provides an analysis of causes why Klebsiella pneumoniae takes a leading place among opportunistic human bacteria. The review includes the history of K. pneumoniae studies, microbiological properties and various Klebsiella-associated types of infections. The molecular and genetic mechanisms of K. pneumoniae virulence and antimicrobial resistance are described in detail. It’s concluded that the main underline cause of K. pneumoniae threat is the potential for developing resistance to all antimicrobial classes.

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