Nature Communications (Jun 2022)

Recovery of neural dynamics criticality in personalized whole-brain models of stroke

  • Rodrigo P. Rocha,
  • Loren Koçillari,
  • Samir Suweis,
  • Michele De Filippo De Grazia,
  • Michel Thiebaut de Schotten,
  • Marco Zorzi,
  • Maurizio Corbetta

DOI
https://doi.org/10.1038/s41467-022-30892-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 18

Abstract

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The authors investigate the influence of brain injury (strokes) on the criticality of neural dynamics using directly measured connectomes and whole-brain models. They show that lesions engender a sub-critical state that recovers over time in parallel with behavior.