Microstructure, biodegradable behavior in different simulated body fluids, antibacterial effect on different bacteria and cytotoxicity of rolled Zn–Li–Ag alloy

Xuemei Xu; Yujiao Lu; Xin Chu; Yang Yan; Ying Liu; Xiangchun Xu; Xier Luo; Liangjian Chen; Ding Li; Tao Xiao; Kun Yu

doi:10.1088/2053-1591/ab7226

Materials Research Express (Jan 2020)

Microstructure, biodegradable behavior in different simulated body fluids, antibacterial effect on different bacteria and cytotoxicity of rolled Zn–Li–Ag alloy

Xuemei Xu,
Yujiao Lu,
Xin Chu,
Yang Yan,
Ying Liu,
Xiangchun Xu,
Xier Luo,
Liangjian Chen,
Ding Li,
Tao Xiao,
Kun Yu

Affiliations

Xuemei Xu: ORCiD; Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China; School of Materials Science and Engineering, Central South University , Changsha 410083, People’s Republic of China
Yujiao Lu: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China; Xiangya Third Hospital, Central South University , Changsha 410013, People’s Republic of China
Xin Chu: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China; School of Materials Science and Engineering, Central South University , Changsha 410083, People’s Republic of China
Yang Yan: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China
Ying Liu: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China; School of Materials Science and Engineering, Central South University , Changsha 410083, People’s Republic of China
Xiangchun Xu: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China
Xier Luo: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China
Liangjian Chen: Xiangya Third Hospital, Central South University , Changsha 410013, People’s Republic of China
Ding Li: The Second XiangYa Hospital, Central South University , Changsha 410011, People’s Republic of China
Tao Xiao: The Second XiangYa Hospital, Central South University , Changsha 410011, People’s Republic of China
Kun Yu: Department of Materials Science and Engineering, Y antai Nanshan University , Yantai 265713, People’s Republic of China; School of Materials Science and Engineering, Central South University , Changsha 410083, People’s Republic of China

DOI: https://doi.org/10.1088/2053-1591/ab7226
Journal volume & issue: Vol. 7, no. 5
p. 055403

Abstract

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Rolled Zn-0.8Li-0.2Ag(wt%) alloy as candidates for biodegradable materials. The biodegradable behavior of Zn-0.8Li-0.2Ag alloy in different solutions (Ringer’s, DMEM, SBF and DMEMp) was investigated. The cytotoxicity of Zn-0.8Li-0.2Ag alloy and its antibacterial properties against staphylococcus aureus, enterobacter faecalis and candida albicans were evaluated. The results showed that Zn-0.8Li-0.2Ag alloy consists of zinc matrix and a LiZn _4 secondary phase. The presence of Cl ^− causes locally corroded of Zn-0.8Li-0.2Ag alloy in Ringer’s solution, and its corrosion resistance is lower than that of the alloy which is uniformly corroded in other solutions containing CO _3 ^2− and PO _4 ^3− . Zn-0.8Li-0.2Ag alloy is non-toxic and exhibits better antibacterial properties than the experimental reference group without silver.

Published in Materials Research Express

ISSN: 2053-1591 (Online)
Publisher: IOP Publishing
Country of publisher: United Kingdom
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials; Technology: Chemical technology
Website: https://iopscience.iop.org/journal/2053-1591

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