Nature Communications (Jul 2020)
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
- Sepideh Sadegh,
- Julian Matschinske,
- David B. Blumenthal,
- Gihanna Galindez,
- Tim Kacprowski,
- Markus List,
- Reza Nasirigerdeh,
- Mhaned Oubounyt,
- Andreas Pichlmair,
- Tim Daniel Rose,
- Marisol Salgado-Albarrán,
- Julian Späth,
- Alexey Stukalov,
- Nina K. Wenke,
- Kevin Yuan,
- Josch K. Pauling,
- Jan Baumbach
Affiliations
- Sepideh Sadegh
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Julian Matschinske
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- David B. Blumenthal
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Gihanna Galindez
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Tim Kacprowski
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Markus List
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Reza Nasirigerdeh
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Mhaned Oubounyt
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Andreas Pichlmair
- Institute of Virology, TUM School of Medicine, Technical University of Munich
- Tim Daniel Rose
- LipiTUM, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Marisol Salgado-Albarrán
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Julian Späth
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Alexey Stukalov
- Institute of Virology, TUM School of Medicine, Technical University of Munich
- Nina K. Wenke
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Kevin Yuan
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Josch K. Pauling
- LipiTUM, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- Jan Baumbach
- Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich
- DOI
- https://doi.org/10.1038/s41467-020-17189-2
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 9
Abstract
Information developed to understand the molecular mechanisms of SARS-CoV-2 infection for predicting drug repurposing candidates is time-consuming to integrate and explore. Here, the authors develop an interactive online platform for virus-host interactome exploration and drug (target) identification.
