Zhongguo linchuang yanjiu (Nov 2023)
Effect of Tiaoshen Shugan acupuncture on migraine and its influence on hemodynamics
Abstract
Objective To investigate the effect of acupuncture treatment of migraine by the method of Tiaoshen Shugan acupuncture. Methods A retrospective study was conducted on 80 migraine patients admitted to Huazhong University of Science and Technology Union Shenzhen Hospital from October 2022 to March 2023. The patients were divided into a control group (n=38) and a research group (n=42) according to different treatment methods. The control group received flunarizine treatment, while the research group received acupuncture treatment with Tiaoshen Shugan method in addition to flunarizine. The treatment efficacy, incidence of adverse reactions, clinical symptom scores before and after 4 weeks of treatment, hemodynamics［blood flow velocity in anterior cerebral artery (ACA), middle cerebral artery (MCA), and posterior cerebral artery (PCA)］, vascular-related bioactive substances ［plasma calcitonin gene-related peptide (CGRP), endothelin-1 (ET-1)］, and quality of life ［migraine-specific quality of life questionnaire (MSQ)］ were compared between the two groups. Results The research group exhibited a higher overall effective rate compared to the control group(92.86% vs 76.32%, P＜0.05). After 4 weeks of treatment, the severity of headaches, associated symptoms, monthly attack frequency, duration of each attack, MCA, ACA, and PCA blood flow velocities, and plasma CGRP and ET-1 levels were significantly reduced compared to before treatment, and the research group showed a greater reduction compared to the control group (P＜0.05). After 3 months of treatment, both groups showed improved MSQ scores compared to before treatment, and the research group had higher scores than the control group (P＜0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P＞0.05). Conclusion Tiaoshen Shugan acupuncture treatment of migraine can effectively relieve clinical symptoms, improve cerebral hemodynamics, regulate the level of vasogenic active mediators, and improve the quality of life, with significant effects and high safety.
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