EGFR-mutant non-small cell lung cancer patients harboring CDK4 amplification show favorable response to afatinib: Two case reports

• Shuting Zhan,
• Bo Cheng,
• Xiwen Liu,
• Jianfu Li,
• Ge Bai,
• Qi Cai,
• Huiting Wang,
• Yang Xiang,
• Chunyan Li,
• Jianxing He,
• Wenhua Liang,
• Peifang Wei

Affiliations

Shuting Zhan

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Bo Cheng

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Xiwen Liu

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Jianfu Li

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Ge Bai

2 National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health & The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Qi Cai

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Huiting Wang

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Yang Xiang

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Chunyan Li

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Jianxing He

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Wenhua Liang

1 Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

Peifang Wei