The use of extracorporeal shock wave therapy along with other non-drug methods in the treatment of chronic prostatitis from the standpoint of modern evidence-based medicine

Abstract

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the most common urogenital pathologies in working men. This disease could significantly negatively affect to the quality of life. The standard drug 3-Astherapy has not a corrective effect in some cases, depending on the phenotype of the disease, other groups of drugs and physiothera-peutic methods of treatment can be used additionally. Currently, the search is underway for the most effective non-drug and drug-based methods of treatment of CP/CPPS. One of these is extracorporeal shock wave therapy (ESWT) and the drug “Longidaza®”. This review analyzes and summarizes the results of large clinical studies evaluating the effectiveness of the use of ESWT in/without combination with drugs, as well as “Longidaza®” in patients with CP/CPPS. The mechanism of action is analyzed in detail and the key effects of the action of ESWT are demonstrated, namely: decrease of pain and dysuria, anti-inflammatory and antibacterial effects, lysis of prostate calcinates and fibrosis.

Keywords

• chronic prostatitis
• chronic pelvic pain syndrome
• extracorporeal shock wave therapy
• “longidaza®”
• bovhyaluronidase azoximer