Nature Communications (Dec 2022)
Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America
- Roxana Zamudio,
- Patrick Boerlin,
- Racha Beyrouthy,
- Jean-Yves Madec,
- Stefan Schwarz,
- Michael R. Mulvey,
- George G. Zhanel,
- Ashley Cormier,
- Gabhan Chalmers,
- Richard Bonnet,
- Marisa Haenni,
- Inga Eichhorn,
- Heike Kaspar,
- Raquel Garcia-Fierro,
- James L. N. Wood,
- Alison E. Mather
Affiliations
- Roxana Zamudio
- Quadram Institute Bioscience, Norwich Research Park
- Patrick Boerlin
- Department of Pathobiology, University of Guelph
- Racha Beyrouthy
- Microbes Intestin Inflammation et Susceptibilité de l’Hôte (M2ISH), Faculté de Médecine, Université Clermont Auvergne
- Jean-Yves Madec
- Unité Antibiorésistance et Virulence Bactériennes, Anses Laboratoire de Lyon, Université de Lyon
- Stefan Schwarz
- Institute of Microbiology and Epizootics, Department of Veterinary Medicine, Freie Universität Berlin
- Michael R. Mulvey
- National Microbiology Laboratory, Public Health Agency of Canada
- George G. Zhanel
- Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba
- Ashley Cormier
- Department of Pathobiology, University of Guelph
- Gabhan Chalmers
- Department of Pathobiology, University of Guelph
- Richard Bonnet
- Microbes Intestin Inflammation et Susceptibilité de l’Hôte (M2ISH), Faculté de Médecine, Université Clermont Auvergne
- Marisa Haenni
- Unité Antibiorésistance et Virulence Bactériennes, Anses Laboratoire de Lyon, Université de Lyon
- Inga Eichhorn
- Institute of Microbiology and Epizootics, Department of Veterinary Medicine, Freie Universität Berlin
- Heike Kaspar
- Department Method Standardisation, Resistance to Antibiotics Unit Monitoring of Resistance to Antibiotics, Federal Office of Consumer Protection and Food Safety
- Raquel Garcia-Fierro
- Unité Antibiorésistance et Virulence Bactériennes, Anses Laboratoire de Lyon, Université de Lyon
- James L. N. Wood
- Department of Veterinary Medicine, University of Cambridge
- Alison E. Mather
- Quadram Institute Bioscience, Norwich Research Park
- DOI
- https://doi.org/10.1038/s41467-022-34970-7
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Extended-spectrum cephalosporin resistance genes in Escherichia coli have spread worldwide. Here, the authors dissect the emergence and distribution of these genes over time, and across geographic location and host species, to better understand their dynamics and mechanisms of transmission.