Nature Communications (Dec 2022)

Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America

  • Roxana Zamudio,
  • Patrick Boerlin,
  • Racha Beyrouthy,
  • Jean-Yves Madec,
  • Stefan Schwarz,
  • Michael R. Mulvey,
  • George G. Zhanel,
  • Ashley Cormier,
  • Gabhan Chalmers,
  • Richard Bonnet,
  • Marisa Haenni,
  • Inga Eichhorn,
  • Heike Kaspar,
  • Raquel Garcia-Fierro,
  • James L. N. Wood,
  • Alison E. Mather

DOI
https://doi.org/10.1038/s41467-022-34970-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Extended-spectrum cephalosporin resistance genes in Escherichia coli have spread worldwide. Here, the authors dissect the emergence and distribution of these genes over time, and across geographic location and host species, to better understand their dynamics and mechanisms of transmission.