European Journal of Case Reports in Internal Medicine (Oct 2017)

Silent Adrenal Pheochromocytoma Coexistent with Corticomedullary Hyperplasia: A Case Incidentally Discovered

  • Luigi Petramala,
  • Federica Olmati,
  • Antonio Concistrè,
  • Vincenza Saraceno,
  • Gino Iannucci,
  • Antonio Ciardi,
  • Giorgio De Toma,
  • Claudio Letizia

DOI
https://doi.org/10.12890/2017_000714
Journal volume & issue
Vol. 4, no. 10

Abstract

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Introduction: Pheochromocytoma (PHEO) is a rare catecholamine-producing tumour arising from chromaffin cells in the sympatho-adrenal system, and can present as asymptomatic adrenal incidentaloma (AI). Patient: We describe the case of a 61-year-old woman with a right adrenal mass incidentally discovered, who was biochemically characterized with subclinical hypercortisolism (SH). The patient was scheduled for adrenalectomy because of increasing seizure of the right adrenal gland with a haemorrhagic and focal pseudocystic appearance macroscopically, incidental histological and immunohistochemical PHEO, and micronodular cortico-adrenal hyperplasia. Discussion: This report describes a rare case of incidental non-functioning PHEO coexisting with corticomedullary hyperplasia and SH.

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