Synthesis and anticancer evaluation of imidazolidine derivatives: study the reaction of imidazolidineiminothione derivatives with amino acids methyl ester

Abstract

Reaction of imidazolidineiminothiones with some amino acids methyl ester afforded imidazopyrazine and imidazolidine derivatives. Some of obtained products were synthesized by nano technology; where this method reduces the reaction time significantly. The evaluation of biological activity of some selected compounds was carried out and some of synthesized compounds displayed anticancer activity.

Keywords

• imidazolidines
• imidazopyrazines
• amino acids
• anticancer