Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

Francesco Di Virgilio; Alba Clara Sarti

doi:10.15252/emmm.201809369

EMBO Molecular Medicine (Aug 2018)

Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

Francesco Di Virgilio,
Alba Clara Sarti

Affiliations

Francesco Di Virgilio: Department of Morphology, Surgery and Experimental Medicine University of Ferrara Ferrara Italy
Alba Clara Sarti: Department of Morphology, Surgery and Experimental Medicine University of Ferrara Ferrara Italy

DOI: https://doi.org/10.15252/emmm.201809369
Journal volume & issue: Vol. 10, no. 8
pp. n/a – n/a

Abstract

Read online

Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.

Published in EMBO Molecular Medicine

ISSN: 1757-4676 (Print); 1757-4684 (Online)
Publisher: Springer Nature
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General); Science: Biology (General): Genetics
Website: https://www.embopress.org/journal/17574684

About the journal