Endocrine Regulations (Oct 2021)

BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population

  • Kamyshna Iryna I.,
  • Pavlovych Larysa B.,
  • Sydorchuk Larysa P.,
  • Malyk Igor V.,
  • Kamyshnyi Aleksandr M.

DOI
https://doi.org/10.2478/enr-2021-0021
Journal volume & issue
Vol. 55, no. 4
pp. 193 – 203

Abstract

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Objective. Brain-derived neurotrophic factor (BDNF) is identified as an important growth factor involved in learning and memory. Patients with Hashimoto’s thyroiditis can suffer from cognitive dysfunction, whereas BDNF is directly regulated by thyroid hormones. It seems reasonable to propose that changes in BDNF expression underlie some of the persistent neurological impairments associated with hypothyroidism.

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