Molecules (Jan 2022)

Novel Antifungal Dimers from the Roots of <em>Taiwania</em> <em>cryptomerioides</em>

  • Ming-Jen Cheng,
  • Ming-Der Wu,
  • Chao-Lin Chang,
  • Hsun-Shuo Chang,
  • Chiou-Fung Chyu,
  • Yueh-Hsiung Kuo

DOI
https://doi.org/10.3390/molecules27020437
Journal volume & issue
Vol. 27, no. 2
p. 437

Abstract

Read online

Five new dimer compounds, namely Taiwaniacryptodimers A–E (1–5), were isolated from the methanol extract of the roots of Taiwania cryptomerioides. Their structures were established by mean of spectroscopic analysis and comparison of NMR data with those of known analogues. Their antifungal activities were also evaluated. Our results indicated that metabolites 1, 2, 4, and 5 displayed moderate antifungal activities against Aspergillus niger, Penicillium italicum, Candida albicans, and Saccharomyces cerevisiae.

Keywords