Advances in Laboratory Medicine (Oct 2020)

CYFRA 21-1 in patients with suspected cancer: evaluation of an optimal cutoff to assess the diagnostic efficacy and prognostic value

  • Garcia-Valdecasas Gayo Sonsoles,
  • Ruiz-Alvarez Maria Jesus,
  • Gonzalez-Gay Daniel,
  • Ramos-Corral Raquel,
  • Marquez-Lietor Eva,
  • Del Amo Nazaret,
  • Plata Maria del Carmen,
  • Guillén-Santos Raquel,
  • Arribas Ignacio,
  • Cava-Valenciano Fernando

DOI
https://doi.org/10.1515/almed-2020-0005
Journal volume & issue
Vol. 1, no. 4
pp. 160 – 5

Abstract

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Chosen cutoff for cytokeratin 19 fragment antigen (CYFRA 21-1) as a tumor biomarker considerably influences its diagnostic and prognostic usefulness. The aim of the present study is to determine an optimal cutoff value for diagnostic validity of CYFRA 21-1 by Lumipulse ® technology in patients with suspected cancer and also to determine if CYFRA 21-1 levels provide prognostic value.

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